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re: Mefloquine Dreams date: June 19, 2000 location: Seattle, WA


Malaria is a widespread disease that affects 400-500 million victims each year, killing over 1 million. Forty percent of the world's population is at risk, notably in Southeast Asia, Africa, India, and Central America. It is caused by a bite from infected mosquitoes. Mild flu-like symptoms appear 2-4 weeks after infection and, if left untreated, can lead to serious illness and death.

Those are the facts. When it comes to prevention, however, things aren't nearly as clear-cut.

Most doctors believe that the best form of prevention is to mix common-sense precaution (bug repellent; long-sleeve shirts; mosquito nets) with a regimen of prophylactic medication. There are three common malaria medications:

  • Mefloquine
  • Chloroquine phosphate
  • Doxycycline
Different strains of malaria are more- and less- tolerant to the different medications. Which drug to take depends entirely on where you are traveling and what outbreaks are occurring at that time. These are constantly changing, so find a good travel doctor who has access to the latest information.

Each of these three drugs has potentially serious side-effects. Mefloquine can cause mild psychotic side-effects. In most people, these are no more severe than "agitation" that's been compared to the effect of a double-tall at Starbucks. Vivid dreams are also a common reaction. Some people, however, report much more severe reactions, often progressive in nature. Chloroquine can cause dizziness, hair thinning, and itching. Doxycycline causes sun hypersensitivity.

Not suprisingly, there is a vocal anti-Mefloquine crowd on the Net. If you believe some of what you read online, you'd leave home armed with nothing more than gin enemas and a fly swatter. I would urge extreme caution when listening to those unprofessional online rantings. Keep in mind the millions of infections that have been prevented by medication compared to isolated reactions of a few travelers.

Me? I decided on Mefloquine and a healthy dose of gin & tonic (taken orally).

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